Prozac and painkiller link to bleeding - The Times 9th October 2007

Taking anti-depressants with painkillers such as ibuprofen has been found to increase the risk of bleeding from the stomach. A survey confirms that selective serotonin reuptake inhibitors such as Prozac double the risk of bleeding from the stomach – but when they are taken with antiinflammatory painkillers the risk is far higher. Over a year, one in every 106 patients taking SSRIs and such painkillers will need hospital admission for this. The survey, published in Alimentary Pharmacology & Therapeutics, was led by Yoon Loke, of the University of East Anglia, working with colleagues in the US.

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